Atlantic salmon (Salmo salar) are anadromous salmonids of major commercial, cultural and recreational importance. They are the primary finfish aquaculture species in Canada, the UK, Scandinavia and Chile. Metabolism, feed conversion efficiency and growth lie at the core of salmonid aquaculture productivity. Efficient nutrient transfer in terms of feed to weight ratios, as well as the provision of non-marine protein sources, are vital to mitigate the impact of salmon farming. Furthermore communicable disease has an increasing impact on farmed fish, with several emergent microbial and macro- pathogens in circulation.
Like the human gut microbiome project, an understanding of the S. salar microbiome will provide insight into the role microbial species have in nutrient absorption and metabolism, immunity and disease. Unlike in humans, where much of the microbiome is transmitted to juveniles within families and social groups, S. salar must selectively recruit all their commensal bacteria from the external environment to cope with the challenges of the varied ecotopes they exploit. One of our research themes is to explore the ontogeny of the S. salar gut microbiota across its natural range and life including juveniles from marine, and freshwater environment.
In aquaculture, Atlantic Salmon face different challenges – in particular from high intensity infection by copepod ectoparasites – Lepeophtheirus species sea lice. Building on our baseline understanding of healthy microbiota – host interactions, next steps include evaluating the role that salmon associated microbiota play in mitigating – or exacerbating – the impact of these pathogens.
This multidisciplinary project will bring together world class Irish and UK fish biologists, population geneticists, microbiologists, bio-informaticians, engineers and major industry partners to determine for the first time the role of salmon gut microbiota in defining host eneretics, paving the way for more sustainable salmon farming.
SalmoSim is a continuous salmon gut fermentation system aimed at simulating microbial communities present in three major gut compartments of salmon: stomach, pyloric caecum, and mid-intestine.
SalmoSim has the capacity to represent generalized marine or freshwater lifecycle stages. We aim to use the system to:
• Understand niche colonisation and microbial community assembly in the salmon gastrointestinal tract.
• Fully characterise the taxonomic diversity and biochemistry of the microbiomes of salmon with divergent energetic phenotypes.
• Develop tailored microbial communities that will maximize nutritional energy harvest from aquaculture feed.
• Predict the impact of novel feeds or feed additives on gut biochemistry and digestibility.
• Act as a test bed for pro-pre-syn-biotic efficacy and drug delivery.
To find out more please click the logo above or visit @SalmoSim